Fungus in the Feet: (LOJMS)- Lupine Publishers

Fungus in the Feet by Krishna Sarma Pathy in LOJ Medical Sciences in Lupine Publishers

Figure 1 Rich or poor, clean or dirty, infections are always attacking the feet. Here are verrucas which were treated by the local doctor with a freezing spray and ointment and for two years nothing happened until they were zapped with 100 shocks on each verruca, energy level 3 with a 20 mm focal head.

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Considerations for Successful Scale-Up To Tox Batches And Phase-Api (Bulk Drugsubstance): LOJMS- Lupine Publishers

Considerations for Successful Scale-Up To Tox Batches And Phase-Api (Bulk Drugsubstance) by
Krishna Sarma Pathy in LOJ Medical Sciences in Lupine Publishers

Practical Considerations in Pharmaceutical Production Scale-Up- This paper is meant to provide a high-level overview of the steps required to prepare the bulk drug substance API. From first-in-human and through each of the clinical trial stages and into commercialization, scale-up of formulation design is a natural part of pharmaceutical development. At each stage of process development, the batch size increases, from laboratory-scale batches that may be quite small to support preclinical and early clinical stages, to pilot batches that are used in process development, and finally to the production-scale batches needed to support commercialization.

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The ins and outs of elimination: (LOJMS) - Lupine Publishers

The ins and outs of elimination by Andrew Hague in LOJ Medical Sciences (LOJMS) in Lupine Publishers

The interdependence of all living things affects human health. Food is more than energy alone. There are varieties of minerals that are balanced by the body according to its needs and what it does not need is expelled. If they remain, they cause problems - Lupine Publishers.

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Cefpodoxime Proxetil and its By-Products: A Comparative Study as Per EP-7: (LOJMS) - Lupine Publishers)

Cefpodoxime Proxetil and its By-Products: A Comparative Study as Per EP-7 by Krishnasarma pathy in LOJ Medical Sciences - LupinePublishers

Cephalosporins are the highly used Broad-spectrum antibiotics, belong to β-lactam class. Cephalosporins resemble penicillin in that they have a β-lactam structure, but the five-member thiazolidine ring characteristic of the penicillin is replaced by a sixmember dihydrothiazine ring. The bactericidal action of beta lactam antibiotics is directly attributable to their ability to react with PBP’s. The research work relates to a by-products during process for the industrial manufacture of Cefpodoxime Proxetil. The drug is registered in USP and belongs to 3rd generation drug. It was discovered by Brotzu in fungus Cephalosporium Acremonium which produces a chemical which show antimicrobial activity. Abraham isolated the three fragmentation patterns of cefpodoximeproxetil. Data from this systematic study will help improve the safety and quality of cefpodoxime proxetil types of cephalosporin antibiotics cephalosporin P, cephalosporin N, cephalosporin C.7-ACA is widely used as the substrate for synthesizing cephalosporinantibiotics. Modification of the 7-ACA side-chains resulted in the development of useful antibiotic agents, and the first agent is Cephalothin (cefalotin) was launched by. Eli Lilly Company in 1964 There are many patents which gives the procedure of Synthesis of Cefpodoxime ProxetilStability of three Cefpodoxime proxetil products available in indian market at fridge temperatures (2-8 °C), room temperature (25 °C) and elevated temperature (42 °C). Flow properties, rheological and the physicochemical parameters of both powder and reconstituted powder were used to evaluate the stability of different brands of Cefpodoxime proxetil available in india. The powder of stability samples was eluted through a C18 column with formic acid-methanol-water as the mobile phase. In total, 15 impurities were characterized in commercial samples, including 7 known impurities and 8 new impurities. The structures of these unknown compounds were deduced via comparison in Lupine Publishers.

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Doctors should be paid more: (LOJMS) - Lupine Publishers

Doctors should be paid more by Andrew Hague in LOJ Medical Sciences (LOJMS) - Lupine Publishers

Only by increasing productivity can earnings be increased. This applies to doctors as much as all trades. Better techniquesenable diseases to be cured that have hitherto been impossible by traditional methods. By these means, a doctor can heal more patients more easily. Thus, a doctor can earn more, and patients be charged less in Lupine Publishers.

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