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 My Theory of the Oxidative-deoxidative Imbalance in life value by Yan Wang in  LOJ Medical Sciences (LOJMS) - Lupine Publishers

I have words the imbalance of the oxidative-deoxidative state of a special substance happen at it is original prefect balance, the words can use to define my theory of the oxidative-deoxidative Imbalance in life value. I have first time to use the word in 2004 at my working speeches at the University of Pennsylvania School of Medicine. The oxidative state means the Reactive oxygen species (ROS) and reactive nitrogen species (RNS) generation with over producing over the deoxidative state in body, also toxic reagents as paraquat and H₂O₂ can induce oxidative stress. In traditional, ROS generation as (OH, O₂-, ROO, RO) have critical role in oxidative stress, then combined RNS generation as (ONOO- , RSNO) can make the oxidative stress in whole meaning at ROS/ RNS induction to interrupt damage DNA construct, cell, lipids, proteins and other macromolecules. In biological state, ROS or RNS are generate in natural to take some important roles at cell signaling and homeostasis functional; under oxidative interruption, over products from endogenous and exogeneous detect deoxidative defend state to maintain balance of the two sides.

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